His career began in the 1960s, racing a Porsche 907. He won the 1968 24 Hours of Daytona. In the 1970s, he was a successful manager in the Deutsche Rennsport Meisterschaft and the European Touring Car Championship. First he managed Ford, then he took the 1972 champion Hans-Joachim Stuck with him to BMW, to found the successful BMW M team. In the 1980s, Neerpasch was in charge of Sauber Mercedes sports car racing team, winning the 24 Hours of Le Mans. He also discovered and taught talents like Michael Schumacher, Karl Wendlinger, and Heinz-Harald Frentzen.